Comments on: Electrophilic Aromatic Substitutions (1) – Halogenation of Benzene https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/ Sat, 29 Jun 2024 03:34:25 +0000 hourly 1 https://wordpress.org/?v=6.6.2 By: ベンゼンのハロゲン化 – 30歳からの進路選択 https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/#comment-698098 Sat, 29 Jun 2024 03:34:25 +0000 https://www.masterorganicchemistry.com/?p=11495#comment-698098 […] 出典：https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenatio… […]

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/#comment-627796 Thu, 19 May 2022 19:55:18 +0000 https://www.masterorganicchemistry.com/?p=11495#comment-627796 In reply to Rajnikant.

This would have to involve a phenyl radical intermediate. Phenyl radicals are known, and they can be made from (for example) aryl halides with reductants like tributyl tin hydride.

]]> By: Rajnikant https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/#comment-627708 Wed, 18 May 2022 03:58:58 +0000 https://www.masterorganicchemistry.com/?p=11495#comment-627708 Can free radical substitution take pace on benzene?

]]> By: Halogenation of Benzene and other Aromatics - npodu https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/#comment-598864 Fri, 19 Mar 2021 11:30:37 +0000 https://www.masterorganicchemistry.com/?p=11495#comment-598864 […] Chlorination and bromination occurs at normal conditions while fluorination is so much fast and exhaustive that it can break all the bonds and iodination is so slow that it is reversible.People also search about: Reactions of Aromatic Molecules: […]

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/#comment-579935 Wed, 06 May 2020 02:27:01 +0000 https://www.masterorganicchemistry.com/?p=11495#comment-579935 In reply to Tal Parness.

Any of the eight C-H bonds can undergo electrophilic aromatic substitution. Your task is to show that this results in only two distinct compounds.

]]> By: Tal Parness https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/#comment-579924 Tue, 05 May 2020 19:10:59 +0000 https://www.masterorganicchemistry.com/?p=11495#comment-579924 how come naphthalene only has 2 derivatives? Shouldn’t there be a derivative on all the sp2 carbons?

]]> By: Waseeq Ur Rehman https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/#comment-575889 Tue, 04 Feb 2020 14:31:23 +0000 https://www.masterorganicchemistry.com/?p=11495#comment-575889 useful material. Well done, thanks

]]> By: Andrea https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/#comment-572500 Fri, 06 Dec 2019 08:20:14 +0000 https://www.masterorganicchemistry.com/?p=11495#comment-572500 Hi James! In this case if I use two equivalents of chlorine will I get a disubstituted benzene? Thanks

]]> By: James https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/#comment-541202 Tue, 23 Oct 2018 19:01:23 +0000 https://www.masterorganicchemistry.com/?p=11495#comment-541202 In reply to Evan.

One phenyl group is attached to a carbonyl (C=O). The other is attached to a CH2 attached to a carbonyl.

Which phenyl group is more activated? : – )

]]> By: Evan https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenation/#comment-534685 Thu, 28 Jun 2018 09:08:26 +0000 https://www.masterorganicchemistry.com/?p=11495#comment-534685 Hello, love the articles. I am studying for a test including this topic, was wondering where would the Bromine attack if there was a phenyl group attached to a ketone attached to a methyl group attached to another phenyl group. I believe it attaches to the phenyl group furthest from the ketone but was not sure.

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